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CHS-828 (GMX1778)

Catalog No.: A12515

NAMPT inhibitor

CHS-828 (GMX1778)

CHS-828 (GMX1778) Chemical Structure

CAS NO. 200484-11-3

CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.

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Biological Activity

CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.
25 nM120 nM(Kd)
In vitro DMSO 64 mg/mL (172.1 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.46 mL 268.92 mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.45 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12515
Actions Inhibitor
CAS No. 200484-11-3
Formula C19H22ClN5O
M. Wt 371.86
Purity >98%
Synonyms GMX1778, GMX-1778, GMX 1778, CHS828, CHS 828

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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