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NF-κB inhibitor
In Stock
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| Target | Activity | Value |
|---|---|---|
| NF-κB | IC50 | 70 nM |
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| HEK293 | IC50 | 0.07 μM | Inhibition of NF-kappaB activation transfected in PMA-stimulated HEK293 cells after 16 hrs by luciferase reporter gene assay | [PMID: 20481485] |
| HEK293 | IC50 | 0.07 μM | Inhibition of antigen receptor-mediated NF-kappaB activity in HEK293 cells after 2 hrs by luciferase reporter gene assay | [PMID: 20153655] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 758679-97-9 |
| Applications | NF-κB inhibitor |
| Formula | C28H39N3O3 |
| Molecular Weight | 465.63 |
| SMILES | CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
