CID-2858522

Catalog No.: A15046

NF-κB inhibitor

CID-2858522

CID-2858522 Chemical Structure

CAS NO. 758679-97-9

CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$90.00
50 mg
$200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.38 mL 214.76 mL
0.5 mM 4.3 mL 21.48 mL 42.95 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15046
Actions Inhibitor
M. Wt 465.63
Formula C28H39N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 758679-97-9
Synonyms CID 2858522, CID2858522
SMILES CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C

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