CID-2858522

Catalog No.: A15046

NF-κB inhibitor

CID-2858522

CID-2858522 Chemical Structure

CAS NO. 758679-97-9

CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.

Availability: In stock

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5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $200.00

Special Price $160.00

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Biological Activity

CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 uM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.38 mL 214.76 mL
0.5 mM 4.3 mL 21.48 mL 42.95 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15046
Actions Inhibitor
CAS No. 758679-97-9
Formula C28H39N3O3
M. Wt 465.63
Solubility DMSO
Purity >98%
Synonyms CID 2858522, CID2858522
SMILES CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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