Fig. 1 · Structure
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CID 5951923
KLF5 Inhibitor
CID 5951923 is a selective inhibitor of Krüppel-like factor 5 (KLF5), demonstrating an IC50 of 603 nM. This compound effectively reduces the proliferation of cancer cells in vitro, making it a valuable tool for studying KLF5's role in cancer biology. Applications include investigating the molecular mechanisms underlying tumorigenesis and evaluating potential therapeutic strategies targeting KLF5 in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 749872-43-3 |
| Applications | KLF5 Inhibitor |
| Formula | C16H18N2O7S |
| Molecular Weight | 382.39 |
| SMILES | O=C(OCC(N(C)C(CC1)CS1(=O)=O)=O)/C=C/C2=CC=CC([N+]([O-])=O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.