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Publications citing Adooq Products
Cilengitide trifluoroacetate Citations (1)
- Yi Han Tan,et al. Complement-activated vitronectin enhances the invasion of nonphagocytic cells by bacterial pathogens Burkholderia and Klebsiella, Cell Microbiol, 2017, Aug;19(8) 28186697
Chemical Information
| Catalog Num | A12371 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 702.7 |
| Formula | C29H41N8O9F3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 199807-35-7 |
| Synonyms | EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497 |
| SMILES code | CC(C)[[email protected]]1C(=O)N[[email protected]](C(=O)NCC(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O |
| Chemical Name | 2-((2S,5R,8S,11S)-5-benzyl-11-(3-((diaminomethylene)amino)propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid |
Description |
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. | ||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.23 mL | 71.15 mL | 142.31mL |
| 0.5 mM | 2.85 mL | 14.23 mL | 28.46 mL |
| 1 mM | 1.42 mL | 7.12 mL | 14.23 mL |
| 5 mM | 0.28 mL | 1.42 mL | 2.85 mL |
*The above data is based on the productmolecular weight 702.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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