Documents & Downloads

Cimdelirsen sodium

GHR Inhibitor

Cimdelirsen sodium is an investigative antisense oligonucleotide designed to inhibit growth hormone receptor (GHR) synthesis through a ligand-conjugated, hepatic-targeted mechanism. This compound effectively reduces the detrimental effects associated with growth hormone (GH) hypersecretion and lowers circulating insulin-like growth factor-1 (IGF-1) levels in patients with acromegaly. Its primary applications include studying the modulation of GH signaling and exploring therapeutic strategies in disorders related to GH excess.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor, Ligand / Binder
CAS Number	2131025-83-5
Applications	GHR Inhibitor
Formula	C₂₉₆H₄₁₅N₈₃Na₂₀O₁₅₂P₂₀S₁₅
Molecular Weight	9128.16
Synonyms	ISIS 766720 sodium; IONIS-GHR-LRx sodium

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.