Fig. 1 · Structure
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Cinnabarinic acid
mGlu4 Agonist
Cinnabarinic acid primarily functions as an orthosteric agonist of the mGlu4 receptor, selectively engaging with residues within its glutamate binding pocket, and exhibiting no significant activity on other mGlu receptors. As an endogenous metabolite of the kynurenine pathway of tryptophan, cinnabarinic acid plays a role in cell apoptosis. This compound is valuable in research exploring mGlu4 receptor signaling and its implications in neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 606-59-7 |
| Applications | mGlu4 Agonist |
| Formula | C14H8N2O6 |
| Molecular Weight | 300.22 |
| SMILES | O=C(C1=C(N)C(C=C2OC3=C(N=C21)C(C(O)=O)=CC=C3)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.