Fig. 1 · Structure
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Cirsilineol
Immunosuppressive Drug
Cirsilineol is a natural flavone compound that selectively inhibits the IFN-γ/STAT1/T-bet signaling pathway in intestinal CD4+ T cells. This compound exhibits significant immunosuppressive and anti-tumor properties. Cirsilineol has been shown to effectively ameliorate T-cell-mediated experimental colitis induced by trinitro-benzene sulfonic acid (TNBS) in mouse models, making it a valuable reagent for research in immunology and cancer therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 41365-32-6 |
| Applications | Immunosuppressive Drug |
| Formula | C18H16O7 |
| Molecular Weight | 344.32 |
| SMILES | O=C1C=C(OC2=CC(OC)=C(C(O)=C12)OC)C3=CC=C(C(OC)=C3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.