Fig. 1 · Structure
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Cirtuvivint
CLK Inhibitor
Cirtuvivint is a potent inhibitor of CDC-like kinases (CLK), exhibiting oral bioavailability. This compound demonstrates significant potential in the modulation of pre-mRNA splicing, which is crucial for understanding various solid tumors. Cirtuvivint is suitable for research focused on cancer biology and therapeutic development targeting CLK pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2143917-62-6 |
| Applications | CLK Inhibitor |
| Formula | C24H25N7O |
| Molecular Weight | 427.50 |
| Synonyms | SM08502 |
| SMILES | O=C(C1=CC(N2CCN(CC2)C)=NC=C1)NC3=NC=C4C=CC(C5=CN(C)N=C5)=CC4=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.