Fig. 1 · Structure

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cis-3-Hydroxyproline

ASCT2 Substrate

Cis-3-Hydroxyproline is a substrate for the Alanine-Serine-Cysteine transporter 2 (ASCT2, SLC1A5) that induces inwardly-directed anion currents. It interacts with key binding site residues, including Asn471, facilitating its transport function. This compound is valuable for studies on cellular metabolism and has applications in melanoma research, contributing to the understanding of tumor biology and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 567-35-1
Applications ASCT2 Substrate
Formula C5H9NO3
Molecular Weight 131.13
SMILES
C(O)(=O)[C@@H]1[C@H](O)CCN1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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