Fig. 1 · Structure
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cis-4-Hydroxy-L-proline
Collagen Production Inhibitor
Cis-4-Hydroxy-L-proline is a proline analog that serves as a collagen production inhibitor by disrupting the deposition of triple helical collagen. This compound exhibits significant effects on cell growth inhibition and has demonstrated the ability to reduce breast tumor growth induced by N-nitrosomethylurea. Additionally, cis-4-Hydroxy-L-proline has been shown to enhance lung compliance and decrease prostate weight, making it valuable in research related to hypoxic pulmonary hypertension and other fibrotic conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 618-27-9 |
| Applications | Collagen Production Inhibitor |
| Formula | C5H9NO3 |
| Molecular Weight | 131.13 |
| SMILES | O=C(O)[C@H](C1)NC[C@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.