Fig. 1 · Structure
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cis,trans-Germacrone
Anticarcinogen
Cis,trans-Germacrone is an isomer of Germacrone, functioning primarily as an anticarcinogen. It demonstrates significant antitumor, antioxidant, and anti-inflammatory properties. Research indicates that cis,trans-Germacrone inhibits the proliferation of lung cancer cells and modulates the Akt/MDM2/p53 signaling pathway, leading to cell cycle arrest at the G1/S phase. This compound serves as a valuable tool for investigating cancer therapies and cell cycle regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 32663-51-7 |
| Applications | Anticarcinogen |
| Formula | C15H22O |
| Molecular Weight | 218.33 |
| SMILES | C/C(C)=C1C(C/C(C)=C\CC/C(C)=C/C\1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.