Citrulline-specific probe-rhodamine hydrate is a fluorescence-based probe targeting citrulline, a metabolite produced from arginine by protein arginine deiminases (PADs). Increased PAD activity is associated with various diseases, resulting in elevated citrulline levels. This probe enables the detection of abnormal PAD activity and can be effectively utilized in animal models, particularly in studies of ulcerative colitis, aiding in the exploration of disease mechanisms and potential therapeutic targets.
Citrulline-specific probe-rhodamine hydrate is a fluorescence-based probe targeting citrulline, a metabolite produced from arginine by protein arginine deiminases (PADs). Increased PAD activity is associated with various diseases, resulting in elevated citrulline levels. This probe enables the detection of abnormal PAD activity and can be effectively utilized in animal models, particularly in studies of ulcerative colitis, aiding in the exploration of disease mechanisms and potential therapeutic targets.
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