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CJ-21,058

SecA Inhibitor

CJ-21,058 is a potent inhibitor of SecA, with an IC50 value of 15 µg/mL. It disrupts the ATP-dependent translocation of precursor proteins across bacterial cell membranes, thereby hindering protein export. This compound exhibits significant antibacterial activity against Gram-positive bacteria, making it a valuable tool for research into bacterial protein transport mechanisms and antimicrobial strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	405072-57-3
Applications	SecA Inhibitor
Formula	C₂₃H₃₃NO₄
Molecular Weight	387.51
SMILES	O/C([C@@]([C@@](CC[C@H]1C)([H])[C@](C1)([H])C=C2C)([C@@H]2/C=C/C)C)=C(C(N3C)=O)\C([C@@H]3CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.