Fig. 1 · Structure
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CK-963
cTnC Activator
CK-963 is a cardiac troponin C (cTnC) activator with an inhibition constant (Ki) of 11.5 μM. This compound enhances cardiac contractility, making it a valuable tool for studying cardiac physiology and potential therapeutic interventions in heart failure research. Its ability to modulate cardiac muscle function underscores its significance in exploring new avenues for cardiovascular disease treatments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2851991-63-2 |
| Applications | cTnC Activator |
| Formula | C27H36N6O5S |
| Molecular Weight | 556.68 |
| SMILES | O=S(C(C=C(C(NC(C)=N1)=O)C1=C2)=C2OCCN3CCOCC3)(NC4=CC=C(N5C[C@H](C)C[C@@H](C)C5)N=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.