CK0106023 is a selective allosteric inhibitor of kinesin spindle protein (KSP) with a Ki value of 12 nM. This compound induces mitotic arrest and growth inhibition across various tumor cell lines, demonstrating significant antitumor activity. Additionally, CK0106023 has shown efficacy in preclinical models, specifically in tumor-bearing mice, making it a valuable reagent for cancer research and therapeutic development.
CK0106023 is a selective allosteric inhibitor of kinesin spindle protein (KSP) with a Ki value of 12 nM. This compound induces mitotic arrest and growth inhibition across various tumor cell lines, demonstrating significant antitumor activity. Additionally, CK0106023 has shown efficacy in preclinical models, specifically in tumor-bearing mice, making it a valuable reagent for cancer research and therapeutic development.
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