Fig. 1 · Structure
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CK7
Cdk2/9 Inhibitor
CK7 is a potent inhibitor of cyclin-dependent kinases Cdk2 and Cdk9. It demonstrates significant biological activity in modulating cell cycle progression and transcriptional regulation. This reagent is particularly useful in research applications focused on cancer biology and the development of novel therapeutics targeting the cell cycle. Additionally, CK7 serves as a synthetic precursor for the production of Nek1 inhibitors BSc5231 and BSc5367.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 507487-89-0 |
| Applications | Cdk2/9 Inhibitor |
| Formula | C14H12N6O2S |
| Molecular Weight | 328.35 |
| SMILES | O=[N+](C1=CC(NC2=NC=CC(C3=C(C)N=C(N)S3)=N2)=CC=C1)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.