Fig. 1 · Structure
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CKK-E12
Ionizable Lipid
CKK-E12 is an ionizable lipid that plays a critical role in the formation of lipid nanoparticles, facilitating the delivery of RNA-based therapeutics. It demonstrates high selectivity for liver parenchymal cells in vivo, making it a valuable tool for targeted gene delivery applications. This compound is essential for research focused on mRNA and siRNA delivery strategies, enhancing the efficacy of RNA therapeutics in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1432494-65-9 |
| Applications | Ionizable Lipid |
| Formula | C60H120N4O6 |
| Molecular Weight | 993.62 |
| SMILES | O=C(C(CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)N1)NC(CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.