Fig. 1 · Structure

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CL-283796

ACAT Inhibitor

CL-283796 is a potent and orally active inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). This compound effectively reduces low-density lipoprotein (LDL) cholesterol levels while not influencing cholesterol absorption, as demonstrated in studies with African green monkeys. CL-283796 is suitable for research focused on hypercholesterolemia and related lipid metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 107376-72-7
Applications ACAT Inhibitor
Formula C28H41ClN2O
Molecular Weight 457.09
SMILES
O=C(NC1=C(C)C=C(Cl)C=C1C)N(CCCCCCC)CC2=CC=C(CCC(C)C)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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