Fig. 1 · Structure
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CL-329167
Angiotensin II Receptor Antagonist
CL-329167 is a potent, orally active competitive antagonist of the angiotensin II receptor, exhibiting an IC50 of 6 nM. This compound is primarily utilized in hypertension research, facilitating the investigation of cardiovascular therapies and the modulation of blood pressure regulation. Its mechanism of action makes CL-329167 a valuable tool for exploring the role of angiotensin II in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 143945-39-5 |
| Applications | Angiotensin II Receptor Antagonist |
| Formula | C30H32N6O2 |
| Molecular Weight | 508.61 |
| SMILES | O=C1N(C(CCCC)=NC2=C1C=C(C=C2)C(OC)(C)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.