Fig. 1 · Structure

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CL4F8-6

Cationic Lipid

CL4F8-6 is an ionizable cationic lipid characterized by a pKa of 6.14. This compound plays a crucial role in the formation of lipid nanoparticles (LNPs) used for mRNA therapeutics, facilitating efficient delivery and cellular uptake of nucleic acids. Its optimized properties make it a valuable tool in the development of RNA-based therapies and vaccines.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2766493-12-1
Applications Cationic Lipid
Formula C51H101NO5
Molecular Weight 808.35
SMILES
O=C(C(CCCCCC)CCCCCC)OCCCCCCC(CCCCN(CCC)CCC)(CCCCCCOC(C(CCCCCC)CCCCCC)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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