Fig. 1 · Structure

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CL5D

SIRT6 Activator

CL5D is a selective activator of the protein deacetylase SIRT6, enhancing its deacetylation activity and catalytic efficiency. By promoting conformational changes, specifically involving the Arg-65 residue, CL5D serves as a valuable tool for investigating the regulatory mechanisms of SIRT6. This compound is applicable in research areas related to metabolism, DNA repair, and aging, facilitating a deeper understanding of SIRT6’s biological functions.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 2488745-53-3
Applications SIRT6 Activator
Formula C29H11Cl7N2O6
Molecular Weight 731.58
SMILES
O=C(C1=CC=C2C(N(C3=CC=C(N(C(C4=C(Cl)C=C(Cl)C=C4Cl)=O)C(C5=C(Cl)C=C(Cl)C=C5Cl)=O)C(Cl)=C3)C(C2=C1)=O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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