Fig. 1 · Structure

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Clausine K

Anticancer Agent

Clausine K is a carbazole alkaloid with notable anticancer properties primarily targeting human hepatoma HepG2 cells. It demonstrates significant cytotoxicity, with an IC50 of 1.05 μg/mL, outperforming the standard chemotherapeutic agent Etoposide, which has an IC50 of 13.40 μg/mL. Isolated from the dried stems of Clausena excavata using chromatographic techniques, Clausine K is valuable for cancer research applications focused on exploring innovative therapeutic agents.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 182261-96-7
Applications Anticancer Agent
Formula C15H13NO4
Molecular Weight 271.27
SMILES
O=C(C1=C(OC)C=C(NC2=C3C=CC(OC)=C2)C3=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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