Fig. 1 · Structure
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Clerodendrin
IL-4/Hex Inhibitor
Clerodendrin is a natural product isolated from Lobelia chinensis, serving as a dual inhibitor of Interleukin-4 (IL-4) and β-hexosaminidase (Hex). This compound exhibits significant biological activity by modulating inflammatory responses through IL-4 inhibition, while also interfering with Hex activity, which is implicated in various cellular processes. Clerodendrin is valuable in research applications focused on immunology and inflammation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 119738-57-7 |
| Applications | IL-4/Hex Inhibitor |
| Formula | C27H26O17 |
| Molecular Weight | 622.49 |
| SMILES | O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(O)=O)O)O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C2OC(C5=CC=C(C=C5)O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.