Cletoquine-d4-1 is a deuterium-labeled derivative of Cletoquine, a significant active metabolite of Hydroxychloroquine. This compound is produced by the liver through the action of CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine-d4-1 exhibits antiviral activity against the chikungunya virus (CHIKV) and possesses antimalarial properties, making it valuable in research applications focused on malaria and autoimmune disease therapies.
Cletoquine-d4-1 is a deuterium-labeled derivative of Cletoquine, a significant active metabolite of Hydroxychloroquine. This compound is produced by the liver through the action of CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine-d4-1 exhibits antiviral activity against the chikungunya virus (CHIKV) and possesses antimalarial properties, making it valuable in research applications focused on malaria and autoimmune disease therapies.
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