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CLK1/4-IN-1

Clk1/4 Inhibitor

CLK1/4-IN-1 is a selective inhibitor of CLK1 and CLK4, displaying IC50 values of 9.7 nM and 6.6 nM, respectively. This compound demonstrates significant growth inhibitory activity against T24 cancer cells, with a GI50 of 1.1 μM. CLK1/4-IN-1 is suitable for research focused on anticancer therapies and the exploration of CLK-related signaling pathways in cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3029431-90-8
Applications	Clk1/4 Inhibitor
Formula	C₁₈H₁₄ClNO₄S
Molecular Weight	375.83
SMILES	O=C(NC(C1=C(C=CC(Cl)=C1)OC)=O)C2=CC3=CC(OC)=CC=C3S2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.