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CLK1/4-IN-2

CLK1/4 Inhibitor

CLK1/4-IN-2 is a selective inhibitor of CLK1 and CLK4, demonstrating an IC50 of 7 nM and 2.3 nM, respectively. This compound induces protein depletion in cancer cells, exhibiting potent anticancer activity. CLK1/4-IN-2 is applicable for research in various cancer types, including breast cancer, monocytic leukemia, bladder cancer, mammary adenocarcinoma, and hepatocellular carcinoma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2101206-26-0
Applications	CLK1/4 Inhibitor
Formula	C₁₈H₁₆FNO₂S
Molecular Weight	329.39
SMILES	O=C(C=1SC=2C=CC(OC)=CC2C1)N(C)CC=3C=CC=C(F)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.