Fig. 1 · Structure
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Clocortolone
Dermatitis Inhibitor
Clocortolone is a synthetic glucocorticoid steroid primarily targeting inflammatory responses. It exhibits potent anti-inflammatory activity, making it suitable for treating conditions such as seborrheic dermatitis, contact dermatitis, atopic dermatitis, and psoriasis. Clocortolone has localized efficacy, as it demonstrates minimal systemic absorption in vivo, adding to its relevance in dermatological research and therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4828-27-7 |
| Applications | Dermatitis Inhibitor |
| Formula | C22H28ClFO4 |
| Molecular Weight | 410.91 |
| SMILES | C[C@@]12[C@@H](C(CO)=O)[C@H](C)C[C@@]1([H])[C@]3([H])C[C@H](F)C4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.