Fig. 1 · Structure
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Clodronic acid
Osteoclastic Bone Resorption Inhibitor
Clodronic acid is a bisphosphonate that selectively targets osteoclastic bone resorption. It induces osteoclast apoptosis, thereby significantly inhibiting bone resorption processes. This compound is widely utilized in research related to osteoporosis and conditions characterized by excessive bone loss, contributing to the maintenance and potential improvement of bone mineral density.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 10596-23-3 |
| Applications | Osteoclastic Bone Resorption Inhibitor |
| Formula | CH4Cl2O6P2 |
| Molecular Weight | 244.89 |
| Synonyms | Clodronate |
| SMILES | ClC(P(O)(O)=O)(Cl)P(O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.