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Clofarabine-5'-diphosphate

Cytotoxin

Clofarabine-5'-diphosphate is a phosphorylated metabolite of Clofarabine, generated by deoxycytidine kinase (dCK). This compound acts as a cytotoxin, exhibiting potent cytotoxic effects on cancer cells by inhibiting DNA synthesis and interfering with DNA repair mechanisms. Clofarabine-5'-diphosphate is primarily utilized in cancer research to explore its therapeutic potential and to study mechanisms of resistance in tumor biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	167620-89-5
Applications	Cytotoxin
Formula	C₁₀H₁₃ClFN₅O₉P₂
Molecular Weight	463.64
Synonyms	Clofarabine-DP
SMILES	NC1=NC(Cl)=NC2=C1N=CN2[C@H]3[C@@H](F)[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.