Fig. 1 · Structure
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Clofezone
Antirheumatic Agent
Clofezone is an antirheumatic agent that inhibits collagen formation, demonstrating effectiveness in targeting rat Chondrus granulomas. This compound is valuable for investigating various rheumatic diseases, particularly rheumatoid arthritis (RA) and ankylosing spondylitis (AS), providing insights into therapeutic strategies and disease mechanisms associated with these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 17449-96-6 |
| Applications | Antirheumatic Agent |
| Formula | C33H41ClN4O4 |
| Molecular Weight | 593.16 |
| Synonyms | Perclusone |
| SMILES | O=C(COC1=CC=C(C=C1)Cl)NCCN(CC)CC.O=C(N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)C2CCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.