Fig. 1 · Structure

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Clopamide

Diuretic Agent

Clopamide is an orally active thiazide-like diuretic agent that primarily targets the sodium-coupled chloride cotransporter SLC12A3. It exhibits significant diuretic activity, leading to enhanced excretion of sodium and water. Clopamide is utilized in research related to hypertension and cardiac failure, providing insights into fluid balance and blood pressure regulation mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 636-54-4
Applications Diuretic Agent
Formula C14H20ClN3O3S
Molecular Weight 345.84
SMILES
O=C(NN1[C@H](C)CCC[C@@H]1C)C2=CC=C(Cl)C(S(=O)(N)=O)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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