Fig. 1 · Structure
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Clorsulon
Flukicidal Agent
Clorsulon is an orally active flukicidal agent that primarily targets glycolysis, the main energy production pathway in flukes. By inhibiting glucose utilization and affecting acetate and propionate formation, particularly in mature Fasciola hepatica, Clorsulon serves as a competitive inhibitor of 3-phosphoglycolate and ATP. This compound is utilized in research focused on liver fluke infections, specifically in calves and sheep, enabling studies of its efficacy against Fasciola hepatica and Fasciola gigantica.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 60200-06-8 |
| Applications | Flukicidal Agent |
| Formula | C8H8Cl3N3O4S2 |
| Molecular Weight | 380.66 |
| Synonyms | L631529; MK401 |
| SMILES | O=S(C1=C(/C(Cl)=C(Cl)\Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.