Clozapine N-oxide

Catalog No.: A15048
5-HT1C receptor antagonist
Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.
Grouped product items
Product Name Price Stock Qty
Clozapine N-oxide 5mg
$50.00
In stock
Clozapine N-oxide 10mg
$80.00
In stock
Clozapine N-oxide 50mg
$280.00
In stock
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Biological Activity
Discription Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.
Product Information
Catalog Num A15048
Formula C18H19ClN4O
Molecular Weight 342.82
CAS Number 34233-69-7
SMILES C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 63 mg/mL (183.77 mM)
Water 63 mg/mL (183.77 mM)
Ethanol 7 mg/mL (20.41 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.17 mL 145.85 mL 291.7 mL
0.5 mM 5.83 mL 29.17 mL 58.34 mL
1 mM 2.92 mL 14.58 mL 29.17 mL
5 mM 0.58 mL 2.92 mL 5.83 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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