Fig. 1 · Structure
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ClpB-IN-1
ClpB Inhibitor
ClpB-IN-1 is a selective inhibitor of ClpB, a chaperone protein involved in protein homeostasis and stress response in bacteria. This compound exhibits significant antibacterial activity by disrupting the function of ClpB, ultimately leading to impaired bacterial growth and survival. ClpB-IN-1 is a valuable tool for researchers investigating the role of protein chaperones in bacterial physiology and has potential applications in the development of new antibacterial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1453172-23-0 |
| Applications | ClpB Inhibitor |
| Formula | C14H10N2O2S2 |
| Molecular Weight | 302.37 |
| SMILES | O=C1/C(C2=CC=CC=C2N1)=C3C(N(C(S/3)=S)CC=C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.