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CM-728

Peroxiredoxin-1 Inhibitor

CM-728 is an oxazepine-naphthoquinone compound that functions as a selective inhibitor of peroxiredoxin-1. It exhibits significant cytotoxic and bactericidal properties, making it a valuable tool for investigating oxidative stress mechanisms. Additionally, CM-728 impacts mitochondrial function, providing insights into its role in cellular oxidative environments and potential therapeutic applications in cancer and microbial resistance research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2925046-28-0
Applications	Peroxiredoxin-1 Inhibitor
Formula	C₂₂H₁₄N₂O₅
Molecular Weight	386.36
SMILES	O=C1C2=C(C(C3=C1C(O)=CC=C3O)=O)N(C4=CC=CN=C4)CC5=C(C=CC=C5)O2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.