CM026 is a selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), demonstrating submicromolar potency. The compound exerts its inhibitory effect through binding to the aldehyde binding pocket, specifically involving a unique glycine residue. CM026 serves as a valuable chemical tool for investigating the role of ALDH1A1 in various pathological conditions and studying its implications in disease research.
CM026 is a selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), demonstrating submicromolar potency. The compound exerts its inhibitory effect through binding to the aldehyde binding pocket, specifically involving a unique glycine residue. CM026 serves as a valuable chemical tool for investigating the role of ALDH1A1 in various pathological conditions and studying its implications in disease research.
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