Fig. 1 · Structure
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CNS 5161
iGluR Antagonist
CNS 5161 is a selective antagonist of the NMDA ion-channel, specifically targeting the NMDA receptor/ion channel site to achieve noncompetitive inhibition of glutamate action. This compound demonstrates significant biological activity in modulating excitatory neurotransmission, making it an important tool for research in neuropharmacology and neurodegenerative disorders. CNS 5161 is particularly relevant for studies investigating the role of glutamate in various neurological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 160754-76-7 |
| Applications | iGluR Antagonist |
| Formula | C16H18ClN3S2 |
| Molecular Weight | 351.92 |
| SMILES | N=C(NC1=CC(SC)=CC=C1Cl)N(C)C2=CC=CC(SC)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.