Cobitolimod sodium

Catalog No.: A35486
TLR-9 Agonist
Cobitolimod sodium is a TLR-9 agonist that exhibits anti-inflammatory properties through its action on immune signaling pathways. This DNA oligonucleotide effectively inhibits Th17 cell activation while enhancing the expression of the anti-inflammatory markers FoxP3 and IL-10. By targeting and inhibiting the IL-17 signaling pathway, Cobitolimod sodium is valuable for research focused on inflammatory diseases and immune modulation.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCobitolimod sodium is a TLR-9 agonist that exhibits anti-inflammatory properties through its action on immune signaling pathways. This DNA oligonucleotide effectively inhibits Th17 cell activation while enhancing the expression of the anti-inflammatory markers FoxP3 and IL-10. By targeting and inhibiting the IL-17 signaling pathway, Cobitolimod sodium is valuable for research focused on inflammatory diseases and immune modulation.
Product Information
Catalog NumA35486
FormulaC185H215N73O105P18S6Na18
Molecular Weight5925.2 (free acid)
CAS Number1527479-55-5
SMILES[Cobitolimod (sodium)]
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