Cobitolimod

Catalog No.: A35491
TLR-9 Agonist
Cobitolimod is a TLR-9 agonist that exhibits anti-inflammatory activity through the modulation of immune responses. It effectively suppresses Th17 cell activity while promoting the expression of anti-inflammatory markers such as FoxP3 and IL-10. This action inhibits the IL-17 signaling pathway, making Cobitolimod valuable for research investigating inflammatory diseases and immune regulation mechanisms.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCobitolimod is a TLR-9 agonist that exhibits anti-inflammatory activity through the modulation of immune responses. It effectively suppresses Th17 cell activity while promoting the expression of anti-inflammatory markers such as FoxP3 and IL-10. This action inhibits the IL-17 signaling pathway, making Cobitolimod valuable for research investigating inflammatory diseases and immune regulation mechanisms.
Product Information
Catalog NumA35491
FormulaC185H233N73O106P18S6
Molecular Weight5925.20
CAS Number1226822-98-5
SMILES[Cobitolimod]
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