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Cochleamycin A

Anticancer Agent

Cochleamycin A is an anticancer agent characterized by its potent inhibitory activity against various tumor cell lines. It demonstrates IC50 values of 1.6 μg/mL for P388, 14.0 μg/mL for HL60, 6.2 μg/mL for K562, 16.5 μg/mL for COL0205, and 19.1 μg/mL for HT29 cells. Additionally, Cochleamycin A exhibits significant antibacterial activity against Gram-positive bacteria, highlighting its potential utility in both oncological and antimicrobial research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	134769-19-0
Applications	Anticancer Agent
Formula	C₂₁H₂₆O₆
Molecular Weight	374.43
SMILES	CC(O[C@@H]1[C@]2([H])[C@@](C[C@@H]1C)([H])[C@]3([H])[C@](C[C@H](C[C@]4([H])CC(/C(C(O4)=O)=C\3)=O)O)([H])C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.