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CoDi2

Covalent Dimeric Molecule

CoDi2 is a covalent dimerization inducer that specifically promotes the irreversible dimerization of proteins fused with O6-alkylguanine-DNA alkyltransferase (AGT, also referred to as SNAP-tag) in live cells. This compound serves as an innovative "sensor" for probing protein-protein interactions, enabling scientists to investigate dynamic biological processes and the functional consequences of dimerization in various research applications. CoDi2's specificity and irreversibility make it a valuable tool for elucidating the roles of protein interactions in cellular networks.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inducer
CAS Number	680622-88-2
Applications	Covalent Dimeric Molecule
Formula	C₄₃H₅₈N₁₂O₁₁
Molecular Weight	918.99
SMILES	NC1=NC(NC=N2)=C2C(OCC3=CC=C(C=C3)COCCOCCOCCOCCNC(NCCOCCOCCOCCOCC4=CC=C(C=C4)COC5=NC(N)=NC6=C5N=CN6)=O)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.