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Cofpropamine

Polyadenylation Inhibitor

Cofpropamine is a polyadenylation inhibitor derived from caffeine, demonstrating its ability to modulate mRNA stability and translation. This compound has been shown to enhance the therapeutic effects of cyclophosphamide in models of rat adjuvant arthritis and mouse collagen arthritis. Its applications in research include the study of mRNA processing and the exploration of therapeutic strategies for inflammatory diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	80539-94-2
Applications	Polyadenylation Inhibitor
Formula	C₁₃H₂₁N₅O₃
Molecular Weight	295.34
SMILES	O=C1C2=C(N(C)C(N1C)=O)N=C(N2C)OCCCN(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.