Fig. 1 · Structure
Documents & Downloads
Complement C1s-IN-1
C1s Inhibitor
Complement C1s-IN-1 is a selective inhibitor of the C1s component of the complement system, demonstrating an IC50 value of 36 nM. This compound exhibits potent activity and possesses the ability to cross the blood-brain barrier, making it valuable for research into neuroinflammatory processes and complement-mediated disorders. Its specificity for C1s positions it as a promising tool for elucidating the role of the complement system in various pathological conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3033831-40-9 |
| Applications | C1s Inhibitor |
| Formula | C22H20F2N6O |
| Molecular Weight | 422.43 |
| SMILES | NC1=C(C(F)=CC(N2C[C@H](C3=NOC(C)=C3)N(C4=CC(F)=CC=C4)CC2)=C5)C5=CN=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.