Conantokin R

Name: Conantokin R
Brand: Adooq Bioscience
SKU: A67283
Rating: 5 (288 reviews)

Catalog No.: A67283

NMDA Antagonist

Conantokin R is a peptide antagonist of the NMDA receptor, exhibiting an IC50 value of 93 nM. This compound demonstrates binding affinity for Zn2+ and Mg2+ ions with dissociation constants of 0.15 μM and 6.5 μM, respectively. Conantokin R is noted for its anticonvulsant properties and has potential applications in studies related to excitotoxicity and neuroprotection.

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Conantokin R 202925-60-8 NMDA Antagonist

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Size	Price	Stock	Qty
2mg	$1,025.00	In stock
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Biological Activity

Description	Conantokin R is a peptide antagonist of the NMDA receptor, exhibiting an IC50 value of 93 nM. This compound demonstrates binding affinity for Zn2+ and Mg2+ ions with dissociation constants of 0.15 μM and 6.5 μM, respectively. Conantokin R is noted for its anticonvulsant properties and has potential applications in studies related to excitotoxicity and neuroprotection.

Product Information

Catalog Num	A67283
Formula	C127H201N35O49S3
Molecular Weight	3098.35
CAS Number	202925-60-8
Sequence	Gly-Glu-{Gla}-{Gla}-Val-Ala-Lys-Met-Ala-Ala-{Gla}-Leu-Ala-Arg-{Gla}-Asn-Ile-Ala-Lys-Gly-Cys-Lys-Val-Asn-Cys-Tyr-Pro (Disulfide bridge:Cys21-Cys25)
Sequence shortening	GE-{Gla}-{Gla}-VAKMAA-{Gla}-LAR-{Gla}-NIAKGCKVNCYP (Disulfide bridge:Cys21-Cys25)
SMILES	CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CN)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC1=O)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O \|@@:135\|
Synonyms	Con-R

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