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Concanamycin D

Lysosomal Acidification Inhibitor

Concanamycin D is a potent lysosomal acidification inhibitor, exhibiting an IC50 value of 0.085 nM. It effectively disrupts lysosomal function by preventing the acidification necessary for enzymatic activity. This compound is utilized in research to study the roles of lysosomes in cellular processes and to investigate the effects of lysosomal dysfunction in various diseases. Its unique mechanism makes it invaluable for exploring autophagy, apoptosis, and the development of lysosomal storage disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	144450-34-0
Applications	Lysosomal Acidification Inhibitor
Formula	C₄₄H₇₂O₁₃
Molecular Weight	809.03
SMILES	O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O[C@H]3C[C@H]([C@@H]([C@@H](C)O3)O)O)[C@H](C)[C@@H](/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.