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Copper ionophore I

Copper Ion Carrier

Copper Ionophore I is a potent copper ion carrier that regulates intracellular copper levels, leading to the induction of cuproptosis in cancer cells such as 4T1 (IC50 = 0.45 μM) and MDA-MB-231 (IC50 = 1.21 μM). This compound elevates reactive oxygen species (ROS) and disrupts mitochondrial function. Additionally, Copper Ionophore I downregulates the expression of key proteins, including FDX1, DLAT, and LIAS, and activates immune-related pathways to enhance T cell infiltration. It is a valuable tool for cancer research, particularly in studies focusing on copper metabolism and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	101264-90-8
Applications	Copper Ion Carrier
Formula	C₁₃H₁₈N₂O₂
Molecular Weight	234.29
SMILES	OC1=C(/C=N/NC(CCCCC)=O)C=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.