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Corthrombin

Catalog No.: A77904
Thrombin Inhibitor
Corthrombin is a highly potent alpha-keto-amide thrombin inhibitor, exhibiting a Ki value of 1 pM. This compound is utilized in the study of cardiovascular diseases, providing valuable insights into thrombin-related mechanisms and potential therapeutic interventions. Its high specificity and efficacy make it an essential tool for research focused on coagulation processes and thrombotic disorders.
Corthrombin 166247-65-0 Thrombin Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCorthrombin is a highly potent alpha-keto-amide thrombin inhibitor, exhibiting a Ki value of 1 pM. This compound is utilized in the study of cardiovascular diseases, providing valuable insights into thrombin-related mechanisms and potential therapeutic interventions. Its high specificity and efficacy make it an essential tool for research focused on coagulation processes and thrombotic disorders.
Product Information
Catalog NumA77904
FormulaC94H137N23O34
Molecular Weight2133.23
CAS Number166247-65-0
SMILESNC(CC(C(NCC(NC(C(NC(CC1=CC=CC=C1)C(NC(C(NC(CCC(O)=O)C(NC(C(C)CC)C(N2C(C(NC(C(NC(CC3=CC=C(C=C3)O)C(NC(CC(C)C)C(O)=O)=O)=O)CCC(O)=O)=O)CCC2)=O)=O)=O)CCC(O)=O)=O)=O)CC(O)=O)=O)=O)NC(CNC(CNC(CNC(CNC(CNC(C(C(NC(C4CCCN4C(C(NC(C(CCC)CCC)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O
SynonymsCVS 995
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Proteases > Thrombin