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Cot-IN-5

COT Inhibitor

Cot-IN-5 is a potent ATP-competitive inhibitor targeting the cancer Osaka thyroid (COT) kinase. It effectively inhibits COT autophosphorylation, making it a valuable tool for studies related to cancer signaling pathways. This compound can be utilized in research aimed at understanding COT's role in oncogenesis and developing novel therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1798303-75-9
Applications	COT Inhibitor
Formula	C₁₈H₁₄N₂O₂
Molecular Weight	290.32
SMILES	OC(/C=C/C1=CC(C2=CC3=C(C=CC=C3)C=C2)=CN=C1N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.