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Cot inhibitor-3

COT Inhibitor

Cot inhibitor-3 is a potent and selective inhibitor of COT kinase, exhibiting an IC50 of 4 nM. This compound effectively suppresses the activity of COT kinase, a key player in various inflammatory processes. Cot inhibitor-3 is primarily utilized in research applications related to cancer and inflammation, making it a valuable tool for studying inflammation-driven conditions and therapeutic mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1984784-12-4
Applications	COT Inhibitor
Formula	C₃₀H₂₈N₈O
Molecular Weight	516.60
SMILES	C[C@H](CN1CCOCC1)NC2=NC3=C(C=C2)C=C(C=C3)N4C5=C(N=C4)C=NC6=CN=C(C7=CC=NC=C7)C=C56

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.