Fig. 1 · Structure

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CP-293019

Dopamine D4 Receptor Antagonist,

CP-293019 is a selective antagonist of the dopamine D4 receptor, characterized by a Ki value of 3.4 nM. This compound effectively inhibits apomorphine-induced hyperactivity in rat models, making it a valuable tool for research into neuropharmacology and the role of dopamine receptors in behavioral studies. Its application extends to studies exploring the mechanisms underlying dopamine-related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 179089-90-8
Applications Dopamine D4 Receptor Antagonist,
Formula C19H22F2N4O
Molecular Weight 360.40
SMILES
FC1=CN=C(N2C[C@](CC[C@@H](COC3=CC=C(F)C=C3)C4)([H])N4CC2)N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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